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Nachum Dafny Selected Research

Methylphenidate (Ritalin)

1/2020Glutamate and dopamine in the VTA participate differently in the acute and chronic effect of methylphenidate.
1/2020The prefrontal cortex and the caudate nucleus respond conjointly to methylphenidate (Ritalin). Concomitant behavioral and neuronal recording study.
1/2019Acute and chronic methylphenidate administration in intact and VTA-specific and nonspecific lesioned rats.
1/2019Glutaminergic signaling in the caudate nucleus is required for behavioral sensitization to methylphenidate.
1/2019Exposure to methylphenidate in adolescence and adulthood modulates cross-sensitization to amphetamine in adulthood in three genetically variant female rat strains.
1/2019Methylphenidate dose-response behavioral and neurophysiological study of the ventral tegmental area and nucleus accumbens in adolescent rats.
1/2018Caudate nucleus neurons participate in methylphenidate function: Behavioral and neuronal recordings from freely behaving adolescent rats.
1/2017Methylphenidate modulates dorsal raphe neuronal activity: Behavioral and neuronal recordings from adolescent rats.
1/2017Comparison of the VTA and LC response to methylphenidate: a concomitant behavioral and neuronal study of adolescent male rats.
1/2017Concomitant behavioral and PFC neuronal activity recorded following dose-response protocol of MPD in adult male rats.
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Nachum Dafny Research Topics

Disease

31Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
01/2020 - 05/2003
1Narcolepsy
01/2020
1Autoimmune Diseases (Autoimmune Disease)
10/2005
1Virus Diseases (Viral Diseases)
10/2005
1Hematologic Neoplasms (Hematological Malignancy)
10/2005
1Chronic Pain
07/2005

Drug/Important Bio-Agent (IBA)

30Methylphenidate (Ritalin)FDA LinkGeneric
01/2020 - 05/2003
11Pharmaceutical PreparationsIBA
01/2019 - 12/2006
3Amphetamine (Amfetamine)FDA LinkGeneric
01/2019 - 09/2004
3Illicit Drugs (Recreational Drugs)IBA
01/2019 - 01/2017
1Dopamine (Intropin)FDA LinkGeneric
01/2019
1Nootropic Agents (Nootropics)IBA
04/2012
1InterferonsIBA
10/2005
1Antiviral Agents (Antivirals)IBA
10/2005
1OligodeoxyribonucleotidesIBA
07/2005
1Formaldehyde (Formol)FDA Link
07/2005
1Cocaine (Cocaine HCl)IBA
09/2004

Therapy/Procedure

3Drug Therapy (Chemotherapy)
01/2017 - 03/2012
1Therapeutics
10/2005